PIR1, a Novel Phosphatase That Exhibits High Affinity to RNA·Ribonucleoprotein Complexes
نویسندگان
چکیده
منابع مشابه
Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase
PIR1 is an atypical dual-specificity phosphatase (DSP) that dephosphorylates RNA with a higher specificity than phosphoproteins. Here we report the atomic structure of a catalytically inactive mutant (C152S) of the human PIR1 phosphatase core (PIR1-core, residues 29-205), refined at 1.20 Å resolution. PIR1-core shares structural similarities with DSPs related to Vaccinia virus VH1 and with RNA ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1998
ISSN: 0021-9258
DOI: 10.1074/jbc.273.32.20347